Name: Amit Bar-Or MD, FCP, FAAN, FANA
Affiliation: Melissa and Paul Anderson President’s Distinguished Professor
Department of Neurology, Perelman School of Medicine
Director, Centre for Neuroinflammation and Experimental Therapeutics
Chief, Division of MS and Related Disorders
University of Pennsylvania (UPenn)
Dr. Bar-Or, a neurologist and neuroimmunologist, was Professor in the Department of Neurology and Neurosurgery, and Associate Director (Clinical and Translational Research) of the Montreal Neurological Institute and Hospital, McGill University, prior to taking on position of Presidential Endowed Chair at the University of Pennsylvania (UPenn/CHOP) where is founder and Director of the Centre for Neuroinflammation and Experimental Therapeutics. His clinical focus is Multiple Sclerosis (MS) and related disorders in both adults and children, and he runs a cellular and molecular Neuroimmunology lab that studies basic principles of immune regulation and immune-neural interaction, in the context of inflammation, injury and repair of the human central nervous system (CNS). Research themes are directed at understanding principles of immune-regulation, elucidation of effector and regulatory mechanisms of distinct immune cell (principally T cell, B cell, and myeloid cell) subsets in CNS inflammatory disease; immune reconstitution, neuroimmune interactions and mode of action of emerging therapies. He is past President of the Canadian Network of MS Clinics (CNMSC) and past member of the Board of Directors of the Federation of Clinical Immunology Societies (FOCIS) where he continues as a member of the Education Committee. He also serves on the Board of Directors of the Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) and on the Steering Committee of the NIH Immune Tolerance Network (ITN).
Pasquini, Juana Maria
Name: Juana Maria Pasquini PhD
Affiliation: Emeritus Professor Biological Chemistry
University of Buenos Aires
Research and Professional Experience
1964-1968:Instructor in Biochemical Pathology. Department of Biochemistry –
1969-1980:Senior Instructor in Biochemical Pathology. Department of Biochemistry.
1969-1981:Assistant Professor in Biochemical Pathology. Department of Biochemistry.
1983-1993: Associate Professor in Biochemical Pathology. Department of Biochemistry
1993:Full Professor. Department of Biological Chemistry.Section on Biochemical Pathology.School de Pharmacy and Biochemistry.University of Buenos Aires.
Other Experience and Professional Memberships
1986-1990: Dean of the School of Pharmacy and Biochemistry – University of Buenos Aires.
1994:Member of the Editorial Board of Developmental Neuroscience.
1995: Elected Council Member of the International Society for Developmental Neuroscience.
2001:Chair of the Local Organizing Committee of the Joint Meeting of the International and American Societies for Neurochemistry
2006:Organizer of the International School of the International Brain Res.
2007:Chairperson of the Committee for the Advancement and Encouragement of Neurochemistry in Latin America (CAENLA). American Society for Neurochemistry
Active Member American Society for Neurochemistry
Active Member Argentine Society for Neurochemistry (founding member).
1971 Faculty Prize – To the best Doctoral Thesis of the year.
1992 National Academy of Science of Buenos Aires Award.
2018Marthe Vogt Award International Soc for Neurochemistry
2018Member of the Latin American Academy of Science.
(Selected from 120 Articles, 180 Abstracts, 8 Book chapters)
Guitart ME, Vence M, Correale J, Pasquini JM, Rosato-Siri MV. Ontogenetic oligodendrocyte maturation through gestational iron deprivation: The road not takenGlia. 2019 Jun 4. doi: 10.1002/glia.23647.
Wies Mancini VSB, Pasquini JM, Correale JD, Pasquini LA. Microglial modulation through colony-stimulating factor-1 receptor inhibition attenuates demyelination.Glia. 2019 ;67:291-308.
Cheli VT, González Santiago DA, Marziali LN, Zamora NN, Guitart ME, Spreuer V, Pasquini JM, Paez PM. The Divalent Metal Transporter 1 (DMT1) is required for iron uptake and normal development of oligodendrocyte progenitor cells.J Neurosci. 2018; 38:9142-9159
Rosato-Siri MV, Marziali L, Guitart ME, Badaracco ME, Puntel M, Pitossi F, Correale J, Pasquini JM. Iron Availability Compromises Not Only Oligodendrocytes But Also Astrocytes and Microglial Cells.Mol Neurobiol.2017 Jan 14.doi:10.1007/s12035-016-0369-2.
The Effects of Prenatal Iron Deficiency and Risperidone Treatment on the Rat Frontal Cortex: A Proteomic Analysis. Farrelly L, Rosato-Siri MV, Föcking M, Codagnone M, Reines A, Dicker P, Wynne K, Farrell M, Cannon M, Cagney G, Pasquini JM, Cotter DR. Proteomics. 2017;17. doi: 10.1002/pmic.201600407.
Combined effects of transferrin and thyroid hormone during oligodendrogenesis In vitro.Marziali LN, Correale J, Garcia CI, Pasquini JM. Glia. 2016;64:1879-91.
Ligand-mediated Galectin-1 endocytosis prevents intraneural H2O2 production promoting F-actin dynamics reactivation and axonal re-growth.Quintá HR, Wilson C, Blidner AG, González-Billault C, Pasquini LA, Rabinovich GA, Pasquini JM.Exp Neurol. 2016 ;283:165-78.
Rinaldi M, Thomas L, Mathieu P, Carabias P, Troncoso MF, Pasquini JM, Rabinovich GA, Pasquini LA. Galectin-1 circumvents lysolecithin-induced demyelination through the modulation of microglial polarization/phagocytosis and oligodendroglial differentiation.Neurobiol Dis. 2016 96:127-143.
Name: Jaclyn Schwarz PhD
Affiliation: Department of Psychological & Brain Science
University of Delaware
Dr. Jaclyn Schwarz received her PhD from the University of Maryland Medical School, where she examined the mechanisms by which testosterone masculinizes neural circuits in the neonatal brain. She continued her training as a postdoctoral fellow at Duke University, where she studied how early-life experiences, including parental care, can program the function of the immune system, and thereby affect later-life brain and behaviors. In her own lab at the University of Delaware, she is currently funded by the NIH to study the mechanisms by which early-life immune activation can disrupt the development of important neural circuits that control learning, and how these mechanisms and effects may be different between males and females. She has been the recipient of the Frank Beach Young Investigator Award from the Society for Behavioral Neuroendocrinology, as well as a NARSAD Young Investigator Award from the Brain and Behavior Research Foundation.
Yong, V. Wee
Name: V. Wee Yong PhD
Hotchkiss Brain Institute,
Departments of Clinical Neurosciences and Oncology at the University of Calgary
Dr. V. Wee Yong is a Professor at the University of Calgary, Canada, and the Canada Research Chair in Neuroimmunology. He co-leads the Multiple Sclerosis (MS) NeuroTeam at the university and he directs the provincial Alberta MS Network. Dr. Yong’s research interests lie in the area of neuroimmunology, neuroprotection and CNS regeneration, and his projects are guided by MS and brain tumors. Dr. Yong has published 290 peer-reviewed manuscripts and his research has been translated into Phase III clinical trials in MS and spinal cord injury. His work has been cited over 19,000 times by other authors (web of science; h-index of 78). Dr. Yong is a past chair of the Medical Advisory Committee of the MS Society of Canada; this and other volunteer activities resulted in him receiving the Queen’s Golden Jubilee Year Medallion. Dr. Yong is on the editorial board of 7 international journals; he is the Honorary Editor-in-Chief of the journal Neuroimmunology and Neuroinflammation. He has been the President of the International Society of Neuroimmunology (2014-2016) and he continues to co-direct the Global Schools of Neuroimmunology. Dr. Yong is an elected fellow of both the Canadian Academy of Health Sciences and the Royal Society of Canada. He is the 2017 Allyn Taylor International Prize in Medicine winner.