Abstracts

Day 1
24 Set 2019
Printed Poster | Session 1

001 – DRUG REPURPOSING: HIGH DOSE HUMAN IMMUNOGLOBULIN G FOR TREATENT OF TRAUMATIC CERVICAL SPINAL CORD INJURY

Jonathon Chon Teng Chio (1)
Institute of Medical Science, University of Toronto, Toronto, Canada (1)
Electronic Poster | Session 1

002 – Assessment of a potential relationship between Herpes simplex virus type-1 latent infection of the central nervous system and host susceptibility to experimental autoimmune encephalomyelitis.

Luisa Fernanda Duarte (1)
Millennium Institute on Immunology and Immunotherapy, Departamento de Genética Molecular y Microbiología, Facultad de Ciencias Biológicas, Pontificia Universidad Católica de Chile, Santiago, Chile (1)
Electronic Poster | Session 1

004 – Rapid plasticity of microglial metabolism sustains immune surveillance of the brain parenchyma.

Louis-Philippe Bernier (1*)
University of British Columbia, Djavad Mowafaghian Centre for Brain Health, Vancouver, Canada (1)
Electronic Poster | Session 1

006 – Regional distribution, density, and morphology of the peripheral myeloid cells invading the murine brain during normal postnatal development

Micaël Carrier (1)
Axe neurosciences, Centre de recherche du CHU de Québec-Université Laval, Faculté de médecine, Université Laval, Québec, Canada (1)
Printed Poster | Session 1

008 – Interleukin-4 promotes corticospinal regeneration in mouse and man

Nicholas Hanuscheck (1)
Department of Neurology, University Medical Center, Johannes Gutenberg University, Mainz, Germany (1)
Printed Poster | Session 1

009 – Implication of Cellular Adhesion Molecules (CAMs) in oligodendrocytes – CD4 T cells interaction

Helene JAMANN (1)
CRCHUM, Neurosciences, Montreal, Canada (1)
Printed Poster | Session 1

010 – Targeting the tumor extracellular matrix as an immune-boosting strategy for malignant gliomas

ROSHINI ARIVAZHAGAN (1)
SUNY UPSTATE MEDICAL UNIVERSITY, NEUROSCIENCE AND PHYSIOLOGY, SYRACUSE, United States (1)
Printed Poster | Session 1

011 – Proteinase-activated receptor-2 (PAR2) blockade attenuates neuroinflammation in a murine experimental autoimmune encephalomyelitis (EAE) multiple sclerosis model

Rahil Eftekhari (1, 2)
Department of Physiology & Pharmacology and Department of Medicine, Snyder Institute for Chronic Diseases, University of Calgary Cumming School of Medicine, Calgary AB Canada T2N 4N1 (1) - Department of Immunology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran (2)
Printed Poster | Session 1

013 – Microglia distinct and disease associated protein signature in ALS.

Romina Barreto-Núñez (1)
Université Laval, Faculty of Medicine, Quebec, Canada (1)
Printed Poster | Session 1

015 – The neuronal IL-1 receptor is necessary and sufficient for stress-induced social withdrawal and working memory deficits

Damon DiSabato (1)
Institute for Behavioral Medicine Research, The Ohio State University, Columbus, United States (1)
Electronic Poster | Session 1

017 – Infection of the central nervous system by Zika virus in a murine model.

William Enlow (1)
CHU de Québec, Université Laval, Axe Microbiologie, Immunologie et Infectiologie, Québec, Canada (1)
Printed Poster | Session 1

023 – Fecal Transplantation from Alcoholic Hepatitis Patients Drives Systemic and Brain Inflammation

Ben Charpentier (1)
Departments of Anatomical Sciences and Neurobiology (1)
Electronic Poster | Session 1

024 – Sex-specific effects of chronic stress on neurovascular health: implication for sex differences in depression

Laurence Dion-Albert (1)
CERVO Brain Research Center, Université Laval, Québec, Canada (1)
Printed Poster | Session 1

027 – Smoking mice: analysis of the effect of cigarette smoke on hippocampal microglia

Fernando Gonzalez Ibanez (1)
Université Laval CRCHU de Québec, Université Laval, Quebec, Canada (1)
Electronic Poster | Session 1

030 – Diurnal Variations in Circulating T-Cell Counts and Phenotype in HIV-Infected Individuals Receiving Viral Suppressive Antiretroviral Therapy

Debashree Chatterjee (1, 2)
Université de Montréal, Faculté de médecine, Départment de microbiologie, infectiologie et immunologie (1) - CHUM-Reseach Centre, Montréal, Québec, Canada (2)
Printed Poster | Session 1

033 – Prospective characterization of children positive for anti-MOG antibodies meeting Multiple Sclerosis diagnostic criteria.

Giulia Fadda (1, 2*)
Montreal Neurological Institute, McGill University, Montreal, QC, Canada (1) - Center for Neuroinflammation and Neurotherapeutics, and Multiple Sclerosis Division, Department of Neurology, Perelman School of Medicine, University of Pennsylvania Philadelphia, PA, USA (2)
Electronic Poster | Session 1

039 – Immunomodulation by dimethyl fumarate after ventral root avulsion and reimplantation

Paula Regina Gelinski Kempe (1)
University of Campinas, Institute of Biology, Campinas, Brazil (1)
Electronic Poster | Session 1

042 – Molecular adaptations of the blood-brain barrier promoting depression or stress resilience

Katarzyna Anna Dudek (1*)
Université Laval & CERVO Brain Research Center, Quebec City (Canada) (1)
Electronic Poster | Session 1

046 – Spinal cord injury severity modulates the development and maintenance of mechanical and thermal hypersensitivity

Courtney Bannerman (1)
Departments of Biomedical & Molecular Sciences (1)
Electronic Poster | Session 1

047 – Agathisflavone (FAB) acts via alpha estrogen receptors to promote remyelination and regulate gliosis in the mouse cerebellar slice lysolecithin demyelination model

MONIQUE MARYLIN ALVES DE ALMEIDA (1, 4)
Department of Biochemistry and Biophysics, Institute of Health Sciences, Federal University of Bahia, Brazil (1) - School of Pharmacy and Biomedical Science, University of Portsmouth, United Kingdom (4)
Electronic Poster | Session 1

050 – Glycolysis drives macrophage migration and subsequent neuropathology in an animal model of multiple sclerosis

Deepak Kumar Kaushik (1)
Hotchkiss Brain Institute, University of Calgary, Calgary, Canada (1)
Electronic Poster | Session 1

052 – Human Pegivirus-1 exacerbates the neuroinflammatory response in patients co-infected with HIV

Matthew Doan (1)
University of Alberta, Neuroscience and Mental Health Institute, Edmonton, Canada (1)
Electronic Poster | Session 1

054 – Dying a Fiery Death: Caspases-3 and -7 Drive Pyroptosis in Human Brain Microglia

Jason Fernandes (1)
University of Alberta, Medical Microbiology and Immunology, Edmonton, Canada (1)
Electronic Poster | Session 1

055 – PERIPHERAL CHARACTERIZATION OF A NEW PROGRESSIVE MODEL OF PARKINSON DISEASE: THE BSSG RAT.

Amandine Isenbrandt (1, 2)
Faculty of Pharmacy, Laval University (1) - CHU de Québec – Laval University research center (2)
Electronic Poster | Session 1

060 – Single-cell profiling of cerebrospinal fluid lymphocytes from monozygotic twins discordant for multiple sclerosis

Julia Hansen (1§)
Institute of Clinical Neuroimmunology, Hospital of the LMU Munich, Munich, Germany (1)
Printed Poster | Session 1

063 – The role of Serine/Arginine-Rich Splicing Factor 3 (SRSF3) as a regulator of immune response after ischemic stroke: sexual dimorphism

Revathy Guruswamy (1)
CERVO Brain Research Centre and Department of Psychiatry and Neuroscience,, Laval University, Quebec, Canada (1)
Printed Poster | Session 1

065 – Immune Cell Activation: Not So Sexy

Timothy Friedman (1)
University of Alberta, Neuroscience and Mental Health Institute, Edmonton, Canada (1)
Printed Poster | Session 1

066 – Helminth-Induced Modulation of Neuroinflammation

Naomi Fettig (1)
University of British Columbia, Microbiology and Immunology, Vancouver, Canada (1)
Electronic Poster | Session 1

067 – Cell adhesion molecule DICAM: a new player in Multiple Sclerosis pathogenesis

Camille Grasmuck (1)
CRCHUM, Department of Neurosciences, Faculty of Medicine, Université de Montreal, Montréal, Canada (1)
Electronic Poster | Session 1

068 – Characterization of the Immunophenotype of Clinically Isolated Syndrome Patients Who Convert or Not To Multiple Sclerosis and the Effect of Cryopreservation

Chieh-Hsin Lee (1)
University of Alberta, Neuroscience and Mental Health Institute, Edmonton, Canada (1)
Printed Poster | Session 1

070 – Diffuse TBI causes Microglia-Dependent Neuronal Dysfunction and Impaired Axonal Conduction

Chelsea Bray (1)
The Ohio State University, Neuroscience, Columbus, United States (1)
Printed Poster | Session 1

073 – Experimental investigation of the role of Epstein-Barr virus infection in a novel humanized mouse model of multiple sclerosis

Jessica R. Allanach (1)
Department of Microbiology & Immunology, University of British Columbia, Vancouver BC, Canada (1)
Printed Poster | Session 1

077 – Arbour Team: Pushing the frontiers of neuroimmunology for thediscovery of novel mechanisms contributing to multiple sclerosis

Yves Carpentier Solorio (1)
University of Montreal-CHUM, Neuroscience, Montreal, Canada (1)
Electronic Poster | Session 1

084 – Neopterin and Neurofilament Light Chain as markers of HIV-associated neurocognitive impairment in plasma and cerebrospinal fluid

Yisel Cantres-Rosario (1)
University of Puerto Rico, Medical Sciences Campus, University of Puerto Rico, Medical Sciences Campus, San Juan, Puerto Rico (1)
Day 2
25 Set 2019
Electronic Poster | Session 2

003 – Proinflammatory T cells drive distinct inflammatory astrocyte profiles

Samantha Schmaul (1)
Johannes Gutenberg University Mainz, University medical center Mainz, Mainz, Germany (1)
Electronic Poster | Session 2

005 – Microglial Repopulation Attenuates Age-Associated Dysfunction Independent of Neuroinflammation

Shane O'Neil (1)
Department of Neuroscience, The Ohio State University, Columbus, United States (1)
Printed Poster | Session 2

007 – Role of blood-brain barrier transport in stress-induced immune response and depression

Fernanda Neutzling Kaufmann (1)
Laval University, Department of Psychiatry and Neuroscience, Faculty of Medicine and CERVO Brain Research Center, Quebec City, Canada (1)
Printed Poster | Session 2

012 – Dissociating sensory from motor: Temporal assessment of pain in experimental autoimmune encephalomyelitis

Julia Segal (1)
Departments of Biomedical & Molecular Sciences (1)
Electronic Poster | Session 2

014 – Elucidating the role of cystatin C in astrocytes in multiple sclerosis

Alexandra Palmer (1)
Hotchkiss Brain Institute, Neuroscience/The University of Calgary, Calgary, Canada (1)
Electronic Poster | Session 2

016 – Key role of the mCSF/CSF1R axis on microglia in the control of herpes simplex virus encephalitis

Olus Uyar (1)
CHU de Québec, Université Laval, Axe Microbiologie-Immunologie et Infectiologie, Québec, Canada (1)
Electronic Poster | Session 2

018 – Analysing recombinant anti-MOG antibodies associated with central nervous system demyelinating disorders

Alicia Zou (1)
Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research, The Children’s Hospital at Westmead, Discipline of Child and Adolescent Health, Sydney Medical School, University of Sydney, Sydney, Australia (1)
Electronic Poster | Session 2

019 – Characterisation of the human MOG antibody response improves the diagnosis of MOG antibody-associated demyelination

Fiona Tea (1, 2)
Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children’s Hospital at Westmead, Sydney, Australia (1) - Discipline of Child and Adolescent Health, Faculty of Medicine and Health, The University of Sydney, Sydney, Australia (2)
Printed Poster | Session 2

020 – Novel Mechanisms of Neurodegeneration in an Animal Model of Multiple Sclerosis

Cole Libner (1, 4, 5)
Department of Health Sciences (1) - Cameco Multiple Sclerosis Neuroscience Research Center (4) - Office of the SK MS Clinical Research Chair, University of Saskatchewan, Saskatoon, SK, Canada (5)
Printed Poster | Session 2

021 – The role of Th17 lymphocytes in drug resistant epilepsy

Oumarou Ouédraogo (1)
Univ. of Montréal, CR CHUM, Montreal, Canada (1)
Printed Poster | Session 2

022 – Immunological Impact of Dietary Methionine Restriction in Preclinical Models of Multiple Sclerosis

Victoria Hannah Mamane (1)
CRCHUM, University of Montreal, Montreal, Canada (1)
Printed Poster | Session 2

025 – Interactions between the host genome and the gut microbiome determine susceptibility to CNS autoimmune disease.

Theresa Montgomery (1)
University of Vermont, Department of Biomedical and Health Sciences, Burlington, United States (1)
Electronic Poster | Session 2

028 – Identification and epitope mapping of autoreactive T cells against the dopamine-2 receptor in paediatric movement and psychiatric disorders

Deepti Pilli (1)
Brain Autoimmunity Lab, Kids Neuroscience Centre, Kids Research, The Children’s Hospital at Westmead, Discipline of Child and Adolescent Health, Sydney Medical School, University of Sydney, Sydney, Australia (1)
Electronic Poster | Session 2

029 – Validating a flow cytometry live cell-based assay to detect myelin oligodendrocyte glycoprotein antibodies for clinical diagnostics

Joseph A. Lopez (1, 2)
Brain Autoimmunity Group, Kids Neuroscience Centre, Kids Research at the Children’s Hospital at Westmead, Sydney, Australia (1) - Discipline of Child and Adolescent Health, The University of Sydney, Sydney, Australia (2)
Printed Poster | Session 2

031 – Endothelial IL-6 signaling is critical for leukocyte recruitment and activation in a model of autoimmune demyelination

Noopur Singh (1, 2)
Neuroscience Unit, University Hospital Centre of Quebec – Laval University, Quebec, Canada (1) - Department of Molecular Medicine, Faculty of Medicine, Laval University, Quebec, Canada (2)
Printed Poster | Session 2

032 – Mechanisms of IgG4 autoantibodies to neurofascins in autoimmune demyelinating neuropathies

Kristina Patterson (1)
Hospital of the University of Pennsylvania, Neurology, Philadelphia, United States (1)
Printed Poster | Session 2

034 – Serum neurofilament light chain predicts long-term clinical outcomes in multiple sclerosis

Simon Thebault (1)
University of Ottawa, The Ottawa Hospital, Ottawa, Canada (1)
Printed Poster | Session 2

036 – Electrical nerve stimulation promotes repair and confers an axon-protective state following a focal demyelinating lesion

Nataliya Tokarska (1)
Cameco MS Neuroscience Research Center, Anatomy, Physiology and Pharmacology/College of Medicine/University of Saskatchewan, Saskatoon, Canada (1)
Electronic Poster | Session 2

037 – Role of beta2-adrenergic receptors (Beta2AR) in the LPS-induced secretion of cytokines by astrocyte

Paulo Santos (1)
Biomedical Science Institute, University of São Paulo, São Paulo, Brazil (1)
Printed Poster | Session 2

038 – The Role of microRNAs in the Multiple Sclerosis-Associated Human Astrocytic Stress Response

Nicholas Kieran (1)
Montreal Neurological Institute, McGill University, Montreal, Canada (1)
Electronic Poster | Session 2

043 – EFFECTS OF ADRENERGIC SIGNALING ON MACROPHAGE ACTIVITY

Beatriz Marton Freire (1)
Federal University of São Paulo, Immunology Division, EPM, São Paulo, Brazil (1)
Printed Poster | Session 2

045 – Circadian rhythm of somatosensation in inbred and outbred mice

Mitra Knezic (1)
Departments of Biomedical & Molecular Sciences and (1)
Electronic Poster | Session 2

051 – Immunomodulatory action of bone marrow cell transplant in sciatic nerve injury

Gonzalo Piñero (1)
CONICET, Universidad de Buenos Aires, CABA, Argentina (1)
Electronic Poster | Session 2

053 – Transcriptional signatures of primary human microglia across the developmental time line at the single cell level

Moein Yaqubi (1)
Neuroimmunology Unit, Montreal Neurological Institute, McGill University (1)
Electronic Poster | Session 2

056 – Impact of aging on enteric and central nervous systems in a rodent model of Parkinson’s disease

Solène Pradeloux (1, 2)
Faculty of Pharmacy, Laval University (1) - CHU de Québec – Laval University research centre (2)
Printed Poster | Session 2

058 – Characterizing IgA+ plasma cell-mediated protection at the T cell effector stage of experimental autoimmune encephalomyelitis

Angela Wang (1)
University of Toronto, Department of Immunology, Toronto, Canada (1)
Printed Poster | Session 2

069 – Development of a New Humanised Mouse Model of Multiple Sclerosis Using NOD/LtSz-scid IL-2Rγc(null) Mice.

Rose-Marie Rebillard (1)
CRCHUM, Département de neurosciences/Université de Montréal, Montreal, Canada (1)
Printed Poster | Session 2

071 – Astrocyte disruption in EAE is associated with axonal injury and demyelination

Kevin Thorburn (1)
University of Alberta, Pharmacology, Edmonton, Canada (1)
Electronic Poster | Session 2

072 – Expression of CD47, a “do not eat me” signal, is upregulated in neurons under pro-inflammatory conditions

Maryam Nakhaei-Nejad (1)
University of Alberta, Department of Medicine, Edmonton, Canada (1)
Electronic Poster | Session 2

075 – Short-term sleep deprivation in mice induces B cell migration to the brain compartment

Ben Korin (1, 2)
Department of Neuroscience (1) - Department of Immunology (2)
Printed Poster | Session 2

076 – Social defeat stress induces expression of cyclooxygenase-2 and prostaglandin production in reactive brain endothelia

Wenyuan Yin (1)
The Ohio State University, Department of Neuroscience, Columbus, United States (1)
Electronic Poster | Session 2

078 – Analysis of genes underlying the development and maintenance of chronic spinal cord injury pain

Olivia Smith (1)
Queen's University, Department of Biomedical and Molecular Sciences, Kingston, Canada (1)
Electronic Poster | Session 2

080 – B cells regulate CD8+ MAIT cell effector functions: implications for multiple sclerosis

Ayman Rezk (1, 2, 4)
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, PA, USA (1) - Center for Neuroinflammation and Experimental Therapeutics, University of Pennsylvania, PA, USA (2) - Neuroimmunology Unit, Montreal Neurological Institute, McGill University, Montreal, Quebec, Canada (4)
Electronic Poster | Session 2

082 – Combined Low carbohydrate Diet – Rituximab extended Honeymoon Period in a GAD positive Polyneuropathy -Type 1 Diabetes Mellitus patient case report

Wolfgang Trillo Alvarez (1)
SINAPSIS, UCSM School of Medicine, Arequipa, Peru (1)
Electronic Poster | Session 2

083 – Anti-CD20 therapy has limited impact on CD11c+ B cells, though overall improves the balance of inflammatory and regulatory B cells in patients with multiple sclerosis

Koji Shinoda (1, 2)
Department of Neurology, Perelman School of Medicine, University of Pennsylvania, PA, USA (1) - Center for Neuroinflammation and Experimental Therapeutics, Perelman School of Medicine, University of Pennsylvania, PA, USA (2)